35th Symposium: Advances in Biomolecular NMR

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The 35th Steenbock Symposium ‘Advances in Biomolecular NMR’ will be held June 26-28, 2011 at the Wisconsin Institutes for Discovery to honor the career of John L. Markley, Steenbock Professor of Biomolecular Structure, Department of Biochemistry, University of Wisconsin–Madison.

Through his service to the NMR community and leadership of the National Magnetic Resonance Facility at Madison (NMRFAM), the Biological Magnetic Resonance Data Bank (BMRB) and the Center for Eukaryotic Structural Genomics, Professor Markley has made enormous contributions to the field of biomolecular NMR.

The Symposium will have presentations from leaders in the field of biological NMR spectroscopy and in various fields of biochemistry who collaborate on protein structure-function studies with Professor Markley and NMRFAM. Topics will include applications of NMR spectroscopy to study the dynamics and structure-function relationships of proteins and nucleic acids, high-throughput structure determination, metabolomics, and natural products. A poster session will provide those attending the symposium an opportunity to present their recent work in biological NMR spectroscopy.

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Registration

To register

35th Steenbock Symposium Registration form

Registration Fees

Registration fee includes admission to talks and poster sessions, abstract book, reception on Sunday, June 26, and continental breakfast and breaks on Monday June 27 and Tuesday June 28. The banquet, not included in the registration fee, will be held on the evening of Monday, June 27, if you have chosen that option.

Fees

Early – Full Registration $200.00 by 05/15/2011
Early – Student Registration $175.00 by 05/15/2011
Banquet – $50.00

Registration Deadlines

Early registration will last until May 15. After May 15 rates will increase $50. The registration deadline is June 15. After that date, you must register at the door.

Poster Abstract Deadline

May 15, 2011

Cancellation Policy

If you cancel before June 15, your registration fee will be refunded, minus a $50 administrative fee. No refunds for cancellations received on or after June 15. To cancel, please call CALS Conference Services at 608-263-1672 or email at conference@cals.wisc.edu.

Registration Questions

Please call CALS Conference Services at 608-263-1672

Abstract Guidelines

Abstract deadline is May 15, 2011.
  1. All abstracts must be in PDF format (see instructions below)
  2. Please submit your PDF abstract as an email attachment and send it tosteenbock35_abstracts@biochem.wisc.edu
  3. Please include your name and telephone number in the body of the email.
  4. If the PDF file is incorrectly formatted you will be contacted for resubmission. See instructions below.
  5. Submission of email attached word processing files, faxed and regular mail submissions cannot be processed and therefore will not be accepted.
  6. The abstracts will be printed, copied, and distributed to registrants. When ready, a pdf file of the final abstracts will also be available on this web site.
  7. No revisions will be accepted after May 15, 2011.
  8. Acknowledgment of an acceptable abstract will be issued by a return email.
Abstract Creation Instructions
  1. Use any word processing program.
  2. Use any computer platform that supports PDF creation.
  3. The abstract, including images, must be a maximum of one page.
  4. Use only 12 pt Times or 12 pt Times New Roman Font throughout the abstract. Do not make the title bigger and the references smaller.
  5. Set up margins of 1.5 inch (3.5 cm) throughout (top, bottom and sides).
  6. Single space the abstract text, with a double space between the title, authors, and text.
  7. Title of abstract must be bold and in upper and lower case, i.e. This is the Abstract Title.
  8. Authors’ names in upper and lower case, i.e. John Doe, Jane Anyone and Jack Somebody.
  9. Underline the presenting author’s name.
  10. Following authors’ names, please list departmental and institutional affiliation, city, state, zip code, and country.
  11. Reference citations can be in any accepted format.
  12. Save your abstract as a PDF file, name the file “the presenting author’s last name.pdf”, and make sure you use the correct settings.
  13. Correct settings can be found on the Adobe web site.

Poster Info

Poster boards are 48 x 48 inches.

Posters should  be put up after registration and during Sunday evening/night prior to close of the session.

Odd numbered posters will be manned on Monday during the poster session
Even numbered posters will be manned on Tuesday during the poster session.

Posters will be on display throughout the symposium and should be taken down by 6:00PM on Tuesday June 28th.

Schedule

Sunday, June 26th

3:00 – 5:00 PM Registration – South atrium

6:30 – 7:30 PM Reception – South atrium

7:30 – 7:45 PM Opening remarks – Forum

7:45 – 9:15 PM Keynote Session: Forum
Session Chair: David Cowburn

James Prestegard, University of Georgia
Combining NMR with Other Technologies: Chemokine Aggregation and GAG Interaction

Kevin Gardner, University of Texas Southwestern
Ligand-regulated Protein/Protein Interactions: Insights Provided by NMR into Nature’s Switches

Monday, June 27th

8:00 – 8:30 AM Light breakfast – South atrium

8:30 AM – 12:05 PM Morning session – Forum
Session Chair: Angela Gronenborn

Gerhard Wagner, Harvard University
Recent Development of NMR Experiments for Challenging Proteins

Cheryl Arrowsmith, University of Toronto
Molecular Recognition by Readers of the Histone Code

Richard Vierstra, University of Wisconsin-Madison
Atomic Perspectives on Phytochrome Photoactivation and Signaling

David Cowburn, Albert Einstein College of Medicine
Intrinsically Disordered Segments – What Can NMR Tell Us about Their Functions in Biology?

10:10 – 10:25 AM Coffee break – South atrium

Mitsuhiko Ikura, University of Toronto
Probing Cancer Cell Signaling by NMR: Structure, Interaction, and Enzymatic Kinetics of Small GTPases

Silvia Cavagnero, University of Wisconsin-Madison
NMR Sensitivity Enhancement by Laser-driven Approaches

Gaetano Montelione, Rutgers University
The Influenza Non-Structural Protein 1.  Biological Insights from Structural Studies

Slobodan Macura, Mayo Foundation
Study of 18O/16O Isotope Labeling Networks in Metabolic Oligo-phosphates by J-decoupled 31P NMR Chemical Shift Correlation Spectroscopy

12:05 – 1:30 PM Lunch – Explore the neighborhood

1:30 – 4:05 Afternoon session – Forum
Session Chair: John Markley

Heinz Ruterjans, University of Frankfurt
45 Years of Biological NMR

Robert Kaptein, Utrecht University
The Lac Repressor: Structure, Dynamics, and Allosteric Interactions

Masatsune Kainosho, Tokyo Metropolitan University
Perspectives of SAIL-related Methods for Studying Structures and Dynamics of Larger Proteins

2:45 – 3:00 Coffee break – South atrium

Gordon Roberts, University of Leicester
A Tale of Talin – Multiple Domains with Different Functions from the Same Fold

Oleg Jardetzky, Stanford University
Relaxation Theory and Protein Dynamics

4:05 – 6:00 Poster session – South atrium

6:30 –7:00 Cocktails

7:00 –Banquet – Forum

Tuesday, June 28th

8:00 – 8:30 AM Light breakfast – South atriu

8:30 AM – 12:05 PM Morning session – Forum
Session Chair: Samuel Butcher

Ad Bax, The National Institutes of Health
Motions of a Fusion Peptide in Lipid Bilayers from Size-Dispersed 15N NMR Relaxation

Angela Gronenborn, University of Pittsburgh School of Medicine
New Members of the CVNH Family and Other Anti-HIV Lectins

Hector Deluca, University of Wisconsin-Madison
The Vitamin D System:  A New NMR Mine

Tim Bugni, University of Wisconsin-Madison
Exploring the Secondary Metabolome of Marine Invertebrate Associated Bacteria

10:10 – 10:25 AM Coffee break – South atrium

Juli Feigon, University of California Los Angeles
The Architecture of Human Telomerase RNA

Samuel Butcher, University of Wisconsin-Madison
Structural Biology of U6 Spliceosomal RNA

Katherine Henzler-Wildman, Washington University in St. Louis
Direct Observation of Conformational Exchange in the Small Multidrug Resistance Transporter, EmrE

Jeffrey Hoch, University of Connecticut Health Center
Maximum Entropy Reconstruction of Nonuniformly Sampled Multidimensional NMR Data

12:05 – 1:30 PM Lunch – Explore the neighborhood

1:30 – 4:15 PM Afternoon session – Forum
Session Chair: William M. Westler

Brian Volkman, Medical College of Wisconsin
Access to the Unfolded State as a Functional Necessity in Intrinsically Folded Proteins

Mark Girvin, Albert Einstein College of Medicine
Bicelles and Peptide-lipid Diskettes for Integral and Membrane Associated Proteins

Andrew Hinck, The Univ. of Texas Health Center at San Antonio
Flexibility and Function in TGF-? Signal Transduction

2:45 – 3:00 PM Coffee break – South atrium

Art Edison, University of Florida
Nematode Chemical Ecology

Michael Reily, Bristol-Myers Squibb
Putting Metabolomics to Practice in Pharmaceutical R&D

Charles Hoogstraten, Michigan State University
Dynamics and Function in Catalytic RNA

4:15 – 4:30 PM Closing remarks: John L. Markley

4:30 – 6:00 PM Poster session – South atrium

Organizers

Dr. Sam Butcher

Dr. Milo Westler

Dr. Eldon Ulrich

Speakers

Cheryl Arrowsmith – University of Toronto
Ad Bax – The National Institutes of Health
Tim Bugni – University of Wisconsin-Madison
Sam Butcher – University of Wisconsin-Madison
Silvia Cavagnero – University of Wisconsin-Madison
David Cowburn – Albert Einstein College of Medicine
Hector DeLuca – University of Wisconsin-Madison
Art Edison – University of Florida
Juli Feigon – University of California Los Angeles
Kevin Gardner – University of Texas Southwestern
Mark Girvin – Albert Einstein College of Medicine
Angela M. Gronenborn – University of Pittsburgh School of Medicine
Katherine Henzler-Wildman – Washington University School of Medicine
Andrew Hinck – The University of Texas Health Science Center at San Antonio
Jeffrey C. Hoch – University of Connecticut Health Center
Charles Hoogstraten – Michigan State University
Mitsu Ikura – University of Toronto
Oleg Jardetzky – Stanford University
Masatsune Kainosho – Tokyo Metropolitan University
Robert Kaptein – Utrecht University
Slobodan Macura – Mayo Foundation
Gaetano Montelione – Rutgers University
James Prestegard – University of Georgia
Michael Reily – Bristol-Myers Squibb
Gordon Roberts – University of Leicester
Heinz Ruterjans – University of Frankfurt
Richard Vierstra – University of Wisconsin-Madison
Brian Volkman    Medical College of Wisconsin
Gerhard Wagner – Harvard University

Sponsors

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Location Info